Apr 12, 2008

ibuprofen

Ibuprofen has many names..tradenames like advil or motrin and many other names around the world..

some of these names are Alfam - 400, Arfen, Bren, Brufen, Embru, Enflem, Febrilix, Ibrumac, Ibubid T.R, Ibucon – 400/600, Ibugesic, Ibugesic SR, Ibugin , Iburin, Ibusynth, Ibusynth Forte, Inflapen CR, Myofen, Norswel, Nuren, Tabalon, Tricofen

Anyone with a history of allergy to ibuprofen, peptic ulcers, gastritis, or asthma should not take ibuprofen. Anyone planning to get pregnant should not take ibuprofen.

people with asthma should not take ibuprofen and this especially includes children..so if you have any health issues, etc ask a doctor.

Those who take aspirin for their heart have to be careful when taking ibuprofen. The ibuprofen has to be taken at least 3-4 hours(i would make it 6) after the aspirin to get the good heart effects of the aspirin. Aspirin causes a permanent change in blood platelets..by making them "more slippery". Ibuprofen can interfere with this effect so it must be take a few hours after the aspirin.

ibuprofen is unique ..has an effect on the tcells and a few other factors.... ibuprofen is the only nsaid that i've found to work with the formula.

Ibuprofen is a cox l and cox II inhibitor.. Cyclooxygenase (cox) are enzymes which make prostaglandins,,,compounds made from fatty acids which are necessarily for health but can present some problems..such as increasing inflammation.

Ibuprofen is not just a COX inhibitor but can also block transcription factors (proteins) of the NF-AT family which control the activation of genes encoding cytokines and also suppressing Tcell activation both of which are directly involved in inflammation.

one 200 mg tablet in the formula is 1/6 the normal adult dose.

It is in the body for 6-8 hours..so with the single dose, most of the day or for 18 hours your body is clear of ibuprofen and in this way its negatives may be reduced by allowing prostaglandin production which then can protect the stomach and heart.

ibuprofen is considered one of the safest nsaids..with a problem incidence in a normal dose (800mg/day) for a month or more in a population of 18-80years of age ..... 4 problems /10,000 users on a study sample of 40,000

long term (years) high dose (1200-1800mg/day is a standard treatment for children with cystic fibrosis and it is considered safe and effective under a doctors supervision.

low dose, long term (3-5yrs) ibuprofen has been shown to reduce the risk of Alzheimer's and colon cancer..probably due to its anti inflammatory nature but those observations alone do not warrant daily dosing.

interestingly, some of the anti inflammatory compounds in olive oil are chemically related to ibuprofen and induce the same taste to the roof of the mouth but you would have to drink a quart of olive oil daily to get the same effect.

finally, if the formula does help and you clear or get some remission...try the ibuprofen every other day or third day...the goal, as with anything, is to take the least amount to do the job..In the past, i have taken more.. and it seems to work less and may aggravate the problem


bj