Lectins may be the instigator....foods high in lectins,,,wheat, rye , potato tomatoes, milk beans, cucumber, peanuts, peas ..i will find a better and more complete list..
This may be why some diets seem to help with inflammation,,,..its not that they give us added nutrition or are a powerhouse of vitamins..., but by their nature they don't include foods that contain inflammatory lectins in large amounts for a sustained period of time.
The paleolithic diet